Issue 8, 2006
From the journal:

Chemical Communications

Baker's yeast-mediated enantioselective reduction of substituted fluorenones

Feng Li,a   Jingnan Cui,*a   Xuhong Qian,*b   Weimin Rena  and  Xingyong Wanga  

* Corresponding authors

a State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116012, China
E-mail: jncui@chem.dlut.edu.cn
Fax: +86-411-83673488
Tel: +86-411-88993872

b Shanghai Key Laboratory of Chemical Biology, East China University of Science and Technology, Shanghai 200237, China
E-mail: xhqian@ecust.edu.cn
Fax: +86-21-64252603
Tel: +86-21-64253589

Abstract

In the presence of DMSO as co-solvent and under vigorous agitation, baker's yeast in water was found to reduce substituted fluorenones to the corresponding fluorenols in good to excellent enantioselectivities.

Graphical abstract: Baker's yeast-mediated enantioselective reduction of substituted fluorenones

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Article information

DOI
https://doi.org/10.1039/B516475C
Article type
Communication
Submitted
21 Nov 2005
Accepted
06 Jan 2006
First published
13 Jan 2006

Chem. Commun., 2006, 865-867

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Baker's yeast-mediated enantioselective reduction of substituted fluorenones

F. Li, J. Cui, X. Qian, W. Ren and X. Wang, Chem. Commun., 2006, 865 DOI: 10.1039/B516475C

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