Issue 13, 2006
From the journal:

Chemical Communications

Disruption of protein–protein interactions using nanoparticles: inhibition of cytochrome c peroxidase†

Halil Bayraktar,a   Partha S. Ghosh,b   Vincent M. Rotello*b  and  Michael J. Knapp*a  

* Corresponding authors

a Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA
E-mail: mknapp@chem.umass.edu
Fax: 413-545-4490
Tel: 413- 545-4001;

b Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA
E-mail: rotello@chem.umass.edu
Fax: 413-545-4490
Tel: 413- 545-2058;

Abstract

Functionalized gold nanoparticles bind selectively to cytochrome c or cytochrome c peroxidase and inhibit enzyme turnover.

Graphical abstract: Disruption of protein–protein interactions using nanoparticles: inhibition of cytochrome c peroxidase

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Article information

DOI
https://doi.org/10.1039/B516096K
Article type
Communication
Submitted
11 Nov 2005
Accepted
12 Jan 2006
First published
21 Feb 2006

Chem. Commun., 2006, 1390-1392

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Disruption of protein–protein interactions using nanoparticles: inhibition of cytochrome c peroxidase

H. Bayraktar, P. S. Ghosh, V. M. Rotello and M. J. Knapp, Chem. Commun., 2006, 1390 DOI: 10.1039/B516096K

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