Issue 4, 2006

Total synthesis of strobilurin B using a hetero-bis-metallated pentadiene linchpin

Abstract

An efficient, six-step stereocontrolled total synthesis of the antifungal agent strobilurin B is reported and was based on a convergent bi-directional coupling featuring a hetero-bis-1,4-metallated pentadiene system as the linchpin.

Graphical abstract: Total synthesis of strobilurin B using a hetero-bis-metallated pentadiene linchpin

Supplementary files

Article information

Article type
Communication
Submitted
06 Oct 2005
Accepted
02 Nov 2005
First published
06 Dec 2005

Chem. Commun., 2006, 423-425

Total synthesis of strobilurin B using a hetero-bis-metallated pentadiene linchpin

R. S. Coleman and X. Lu, Chem. Commun., 2006, 423 DOI: 10.1039/B514233D

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