Issue 2, 2006
From the journal:

Chemical Communications

Protonated N′-benzyl-N′-prolyl proline hydrazide as highly enantioselective catalyst for direct asymmetric aldol reaction†

Chuanling Cheng,ade   Jian Sun,*a   Chao Wang,ae   Yu Zhang,ae   Siyu Wei,a   Fan Jiangb  and  Yundong Wu*bc  

* Corresponding authors

a Chengdu Institute of Biology, Chinese Academy of Sciences, China
E-mail: sunjian@cib.ac.cn
Fax: +86-28-85222753
Tel: +86-28-85211220

b College of Chemistry, Peking University, China

c Department of chemistry, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, China

d Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu

e Graduate School of Chinese Academy of Sciences, Beijing, China

Abstract

Protonated N′-benzyl-N′-L-prolyl-L-proline hydrazide has been developed as a highly enantioselective catalyst for the asymmetric direct aldol reaction of aromatic aldehydes with ketones.

Graphical abstract: Protonated N′-benzyl-N′-prolyl proline hydrazide as highly enantioselective catalyst for direct asymmetric aldol reaction

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Article information

DOI
https://doi.org/10.1039/B511992H
Article type
Communication
Submitted
24 Aug 2005
Accepted
18 Oct 2005
First published
18 Nov 2005

Chem. Commun., 2006, 215-217

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Protonated N′-benzyl-N′-prolyl proline hydrazide as highly enantioselective catalyst for direct asymmetric aldol reaction

C. Cheng, J. Sun, C. Wang, Y. Zhang, S. Wei, F. Jiang and Y. Wu, Chem. Commun., 2006, 215 DOI: 10.1039/B511992H

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