Catalytic investigations of carbon–carbon bond-forming reactions by a hydroxyapatite-bound palladium complex
Abstract
A new type of hydroxyapatite-bound palladium complex (PdHAP-1) was synthesized by treatment of a nonstoichiometric Ca-deficient hydroxyapatite, Ca9(HPO4)(PO4)5(OH), with PdCl2(PhCN)2 in acetone solution. Characterization by means of physicochemical methods revealed that a monomeric PdII phosphate complex could be generated at a Ca-deficient site, which displayed outstanding catalytic activities for the Mizoroki–Heck reaction and Suzuki–Miyaura coupling reaction of aryl bromides. The remarkably high catalytic activity of the hydroxyapatite