Issue 5-6, 2005
From the journal:

Molecular BioSystems

Anomalous reflection of gold applicable for a practical protein-detecting chip platform†

Sinya Watanabe,a   Kenji Usui,a   Kin-ya Tomizaki,a   Kotaro Kajikawab  and  Hisakazu Mihara*a  

* Corresponding authors

a The COE21 Program and Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama 226-8501, Japan
E-mail: hmihara@bio.titech.ac.jp
Fax: +81-45-924-5833
Tel: +81-45-924-5756

b Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Yokohama 226-8502, Japan

Abstract

A simple, convenient and label-free fiber optic detection system based on the characteristic property, ‘anomalous reflection (AR)’ of gold was developed and preliminary experiments showed that the AR signals were sensitive enough to monitor protein–peptide interactions on solid surfaces.

Graphical abstract: Anomalous reflection of gold applicable for a practical protein-detecting chip platform

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Article information

DOI
https://doi.org/10.1039/B513075C
Article type
Communication
Submitted
14 Sep 2005
Accepted
20 Oct 2005
First published
03 Nov 2005

Mol. BioSyst., 2005,1, 363-365

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Anomalous reflection of gold applicable for a practical protein-detecting chip platform

S. Watanabe, K. Usui, K. Tomizaki, K. Kajikawa and H. Mihara, Mol. BioSyst., 2005, 1, 363 DOI: 10.1039/B513075C

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