Issue 2, 2005

Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

Abstract

Disulfiram, a drug used to treat alcoholism, has recently been indicated to play a primary as well as an adjuvant role in the treatment of many cancers and in the reversal of fungal drug-resistance. This review discusses the molecular mechanism of action of disulfiram and its potential use in the treatment of human cancers and fungal infections.

Graphical abstract: Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

Article information

Article type
Review Article
Submitted
30 Mar 2005
Accepted
16 May 2005
First published
26 May 2005

Mol. BioSyst., 2005,1, 127-134

Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

Z. E. Sauna, S. Shukla and S. V. Ambudkar, Mol. BioSyst., 2005, 1, 127 DOI: 10.1039/B504392A

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