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Issue 2, 2005
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Evidence for a hydrogen abstraction mechanism in P450-catalyzed N-dealkylations

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Abstract

The experimental evidence presented in this manuscript suggest against the widely accepted single electron/proton transfer mechanism for P450 catalyzed N-dealkylations and provides strong support for a hydrogen atom abstraction mechanism.

Graphical abstract: Evidence for a hydrogen abstraction mechanism in P450-catalyzed N-dealkylations

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Publication details

The article was received on 09 Aug 2004, accepted on 23 Sep 2004 and first published on 24 Nov 2004


Article type: Communication
DOI: 10.1039/B412221F
Citation: Chem. Commun., 2005,0, 265-267
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    Evidence for a hydrogen abstraction mechanism in P450-catalyzed N-dealkylations

    M. Bhakta, P. F. Hollenberg and K. Wimalasena, Chem. Commun., 2005, 0, 265
    DOI: 10.1039/B412221F

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