Issue 39, 2005
From the journal:

Chemical Communications

A novel spin trap for targeting sulfhydryl-containing polypeptides†

Yang Ping Liu,a   Yi Qiong Ji,a   Yu Guang Song,a   Ke Jian Liu,*b   Bin Liu,a   Qiu Tiana  and  Yang Liu*a  

* Corresponding authors

a State Key Laboratory for Structural Chemistry of Unstable Species, Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China
E-mail: yliu@iccas.ac.cn
Fax: +86 10 62559373
Tel: +86 10 62571074

b College of Pharmacy, University of New Mexico, 2502 Marble NE, Albuquerque, USA
E-mail: jliu@unm.edu
Fax: (505) 272-6749
Tel: (505) 272-9546

Abstract

A novel spin trap containing an iodoacetamide group has been synthesized and then used to target polypeptides, i.e. glutathione and bovine serum albumin, by which the resulting covalently bonded bioconjugates exhibit great potential for the application of spin trapping of transient radicals in biological systems.

Graphical abstract: A novel spin trap for targeting sulfhydryl-containing polypeptides

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B509903J
Article type
Communication
Submitted
14 Jul 2005
Accepted
27 Aug 2005
First published
07 Sep 2005

Chem. Commun., 2005, 4943-4945

Permissions

Request permissions

A novel spin trap for targeting sulfhydryl-containing polypeptides

Y. P. Liu, Y. Q. Ji, Y. G. Song, K. J. Liu, B. Liu, Q. Tian and Y. Liu, Chem. Commun., 2005, 4943 DOI: 10.1039/B509903J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements