Issue 39, 2005
From the journal:

Chemical Communications

One-pot synthesis of benzolactones and lactamsvia a cobalt-catalyzed regioselective [2 + 2 + 2] cocyclotrimerization of alkynyl alcohols and amines with propiolates†

Hong-Tai Chang,a   Masilamani Jeganmohana  and  Chien-Hong Cheng*a  

* Corresponding authors

a Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan
E-mail: chcheng@mx.nthu.edu.tw
Fax: 886-3-5724698
Tel: 886-3-5721454

Abstract

An efficient method for the synthesis of benzolactones and benzolactams via a cobalt-catalyzed [2 + 2 + 2] cocyclotrimerization of alkynyl alcohols and alkynyl amines with propiolates is described.

Graphical abstract: One-pot synthesis of benzolactones and lactams via a cobalt-catalyzed regioselective [2 + 2 + 2] cocyclotrimerization of alkynyl alcohols and amines with propiolates

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Article information

DOI
https://doi.org/10.1039/B509731B
Article type
Communication
Submitted
08 Jul 2005
Accepted
16 Aug 2005
First published
08 Sep 2005

Chem. Commun., 2005, 4955-4957

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One-pot synthesis of benzolactones and lactams via a cobalt-catalyzed regioselective [2 + 2 + 2] cocyclotrimerization of alkynyl alcohols and amines with propiolates

H. Chang, M. Jeganmohan and C. Cheng, Chem. Commun., 2005, 4955 DOI: 10.1039/B509731B

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