Issue 37, 2005
From the journal:

Chemical Communications

Combining two-directional synthesis and tandem reactions: desymmetrisation by intramolecular cycloaddition/triazoline fragmentation†‡

Martin Rejzek,a   Robert A. Stockman,*a   Jan H. van Maarseveenb  and  David L. Hughesc  

* Corresponding authors

a School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, UK
E-mail: r.stockman@uea.ac.uk
Fax: 44 (0)1603 592005
Tel: +44 (0) 1603 593890

b Institute of Molecular Chemistry, University of Amsterdam, Niewe Achteragracht 129, 1018 WS Amsterdam, The Netherlands
E-mail: jvm@science.uva.nl
Fax: (+31) (0) 20 5255670
Tel: (+31) (0)20 5255671

c X-Ray Crystallography Centre, School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, UK

Abstract

A tandem azide formation/intramolecular cycloaddition/triazoline fragmentation/Michael addition, which results in a non-symmetrical quinolizidine from an acyclic symmetrical precursor, is presented.

Graphical abstract: Combining two-directional synthesis and tandem reactions: desymmetrisation by intramolecular cycloaddition/triazoline fragmentation

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Article information

DOI
https://doi.org/10.1039/B508969G
Article type
Communication
Submitted
24 Jun 2005
Accepted
18 Aug 2005
First published
31 Aug 2005

Chem. Commun., 2005, 4661-4662

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Combining two-directional synthesis and tandem reactions: desymmetrisation by intramolecular cycloaddition/triazoline fragmentation

M. Rejzek, R. A. Stockman, J. H. van Maarseveen and D. L. Hughes, Chem. Commun., 2005, 4661 DOI: 10.1039/B508969G

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