Issue 31, 2005

A novel nucleophilic approach to 1-alkyladenosines. A two-step synthesis of [1-15N]adenosine from inosine

Abstract

A novel ANRORC mechanism in the reaction of 1-(2,4-dinitrobenzenesulfonyl)inosines with amines has allowed the preparation of 1-alkyladenosines and [1-15N]adenosines in a straightforward way from inosines.

Graphical abstract: A novel nucleophilic approach to 1-alkyladenosines. A two-step synthesis of [1-15N]adenosine from inosine

Supplementary files

Article information

Article type
Communication
Submitted
13 Apr 2005
Accepted
09 Jun 2005
First published
07 Jul 2005

Chem. Commun., 2005, 3968-3970

A novel nucleophilic approach to 1-alkyladenosines. A two-step synthesis of [1-15N]adenosine from inosine

M. Terrazas, X. Ariza, J. Farràs and J. Vilarrasa, Chem. Commun., 2005, 3968 DOI: 10.1039/B505183E

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