Issue 8, 2005
From the journal:

Chemical Communications

Cationic polyhedral oligomeric silsesquioxane (POSS) units as carriers for drug delivery processes†

Catherine McCusker,a   Joseph B. Carrollb  and  Vincent M. Rotello*b  

* Corresponding authors

a Department of Molecular and Cellular Biology, The University of Massachusetts, Amherst, USA

b Department of Chemistry, The University of Massachusetts, Amherst, USA
E-mail: rotello@chem.umass.edu
Fax: +1 413 545 4490
Tel: +1 413 545 4865

Abstract

Quaternary ammonium functionalized polyhedral oligomeric silsesquioxane (OctaAmmonium–POSS®) units, widely employed as additives in ceramic and polymeric systems, possess many attributes which make them attractive as biocompatible drug carriers: nanoscale size, three-dimensional functionality, efficient cellular uptake, low toxicity, and high solubility.

Graphical abstract: Cationic polyhedral oligomeric silsesquioxane (POSS) units as carriers for drug delivery processes

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Article information

DOI
https://doi.org/10.1039/B416266H
Article type
Communication
Submitted
20 Oct 2004
Accepted
22 Nov 2004
First published
10 Jan 2005

Chem. Commun., 2005, 996-998

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Cationic polyhedral oligomeric silsesquioxane (POSS) units as carriers for drug delivery processes

C. McCusker, J. B. Carroll and V. M. Rotello, Chem. Commun., 2005, 996 DOI: 10.1039/B416266H

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