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Issue 12, 2004
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Synthesis and application in asymmetric C–C bond formation of solution phase ligand libraries of monodentate phosphoramidites

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Abstract

A library of 96 unique monodentate phosphoramidite ligands has been synthesized in solution and used in the asymmetric conjugate addition of potassium vinyltrifluoroborate to enones resulting in up to 88% ee.

Graphical abstract: Synthesis and application in asymmetric C–C bond formation of solution phase ligand libraries of monodentate phosphoramidites

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Supplementary files

Article information


Submitted
02 Apr 2004
Accepted
12 May 2004
First published
25 May 2004

Org. Biomol. Chem., 2004,2, 1682-1684
Article type
Communication

Synthesis and application in asymmetric C–C bond formation of solution phase ligand libraries of monodentate phosphoramidites

A. Duursma, L. Lefort, J. A. F. Boogers, A. H. M. de Vries, J. G. de Vries, A. J. Minnaard and B. L. Feringa, Org. Biomol. Chem., 2004, 2, 1682
DOI: 10.1039/B404996A

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