Issue 11, 2004
From the journal:

Organic & Biomolecular Chemistry

New phenylselanyl group activation: synthesis of aziridines and oxazolidin-2-ones†

Catherine Miniejew,a   Francis Outurquin*a  and  Xavier Pannecouckea  

* Corresponding authors

a Université et INSA de ROUEN, IRCOF, UMR CNRS6014, 1 rue Tesnière, 76131 Mont Saint-Aignan, France
E-mail: francis.outurquin@univ-rouen.fr
Fax: (33) 2.35.52.29.59
Tel: (33) 2.35.52.24.27

Abstract

After the study of different phenylselanyl group activators, halogenation by N-bromosuccinimide (NBS) has been shown to be the most suitable manner for cyclizing β-phenylselanyl amines into aziridines and also enabled production of oxazolidin-2-ones from N-Boc β-phenylselanyl amines in excellent yield.

Graphical abstract: New phenylselanyl group activation: synthesis of aziridines and oxazolidin-2-ones

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Article information

DOI
https://doi.org/10.1039/B406566M
Article type
Communication
Submitted
30 Apr 2004
Accepted
30 Apr 2004
First published
11 May 2004

Org. Biomol. Chem., 2004,2, 1575-1576

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New phenylselanyl group activation: synthesis of aziridines and oxazolidin-2-ones

C. Miniejew, F. Outurquin and X. Pannecoucke, Org. Biomol. Chem., 2004, 2, 1575 DOI: 10.1039/B406566M

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