Synthesis and cholera toxin binding properties of multivalent GM1 mimics†
Abstract
Dendrimers based on the 3,5-di-(2-aminoethoxy)-benzoic acid branching unit were used to attach multiple copies of a GM1 mimic for inhibition of cholera
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* Corresponding authors
a
Dipartmento di Chimica Organica e Industriale, via Venezian 21, 20133 Milano, Italy
Fax: +39-02-50314092
Tel: anna.bernardi@unimi.it
b
Department of Medicinal Chemistry, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80082, NL-3508 TB Utrecht, The Netherlands
E-mail:
r.j.pieters@pharm.uu.nl
Fax: +31-30-253 6655
Dendrimers based on the 3,5-di-(2-aminoethoxy)-benzoic acid branching unit were used to attach multiple copies of a GM1 mimic for inhibition of cholera
D. Arosio, I. Vrasidas, P. Valentini, R. M. J. Liskamp, R. J. Pieters and A. Bernardi, Org. Biomol. Chem., 2004, 2, 2113 DOI: 10.1039/B405344C
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