Issue 6, 2004

Synthesis of 1S,5R- and 1R,5S-glycoluriles by diastereospecific α-ureidoalkylation of (S)/(R)-N-carbamoyl-α-amino acids with 4,5-dihydroxyimidazolidin-2-one

Abstract

A diastereospecific method for the synthesis of individual enantiomers of 1S,5R- and 1R,5S-glycoluriles has been developed based on the α-ureidoalkylation of (S)/(R)-N-carbamoyl-α-amino acids with 4,5-dihydroxyimidazolidin-2-one.

Article information

Article type
Communication
Submitted
29 Sep 2004

Mendeleev Commun., 2004,14, 253-255

Synthesis of 1S,5R- and 1R,5S-glycoluriles by diastereospecific α-ureidoalkylation of (S)/(R)-N-carbamoyl-α-amino acids with 4,5-dihydroxyimidazolidin-2-one

I. E. Chikunov, A. N. Kravchenko, P. A. Belyakov, K. A. Lyssenko, V. V. Baranov, O. V. Lebedev and N. N. Makhova, Mendeleev Commun., 2004, 14, 253 DOI: 10.1070/MC2004v014n06ABEH002050

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