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Issue 6, 2004
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Macro-to-micro interfaces for microfluidic devices

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Since the concept of miniaturized total analysis systems (μTAS) was invented, a great number of microfluidic devices have been demonstrated for a variety of applications. However, an important hurdle that still needs to be cleared is the connection of a microfluidic device with the rest of the world, which is often referred to as the macro-to-micro interface, interconnect, or world-to-chip interface. In this review, we will examine the methods used by pioneers in the field and other investigators, review the approaches for capillary electrophoresis-based devices and those using pneumatic pumping, and present additional discussion on interface standardization and choosing and designing interconnects for your applications.

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The article was received on 13 Jul 2004, accepted on 12 Oct 2004 and first published on 10 Nov 2004

Article type: Critical Review
DOI: 10.1039/B410720A
Lab Chip, 2004,4, 526-533

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    Macro-to-micro interfaces for microfluidic devices

    C. K. Fredrickson and Z. H. Fan, Lab Chip, 2004, 4, 526
    DOI: 10.1039/B410720A

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