Tuning a reaction using two-site catalysis and far-from-equilibrium conditions

Abstract

We show that a given kinetic mechanism, appropriate for describing the evolution of concentrations in a two-site catalysis, exhibits various properties when maintaining the system far from equilibrium and varying the order of magnitude of the rate constants: tuning of reaction yield, autocatalysis and kinetic proofreading are obtained. The model, involving molecules with two coupled reactive sites, gives some hints to design simple artificial systems possessing complex properties of living systems.