Issue 23, 2004
From the journal:

Chemical Communications

Ensemble hybridisation – a new method for exploring sequence dependent fluorescence of dye–nucleic acid conjugates

Olaf Köhler,a   Dilip Venkatrao Jarikotea  and  Oliver Seitz*a  

* Corresponding authors

a Institut für Chemie, Humboldt-Universität zu Berlin, Brook-Taylor-Str. 2, D-12489 Berlin, Germany
E-mail: oliver.seitz@chemie.hu-berlin.de.
Fax: 0049 30 20937266
Tel: 0049 30 20937446

Abstract

The fluorescence of thiazole orange as artificial base in PNA was investigated in a nearest neighbour analysis; library-to-library hybridisation allowed the identification of probe sequences suitable for homogeneous DNA detection.

Graphical abstract: Ensemble hybridisation – a new method for exploring sequence dependent fluorescence of dye–nucleic acid conjugates

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Article information

DOI
https://doi.org/10.1039/B411877D
Article type
Communication
Submitted
03 Aug 2004
Accepted
13 Sep 2004
First published
14 Oct 2004

Chem. Commun., 2004, 2674-2675

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Ensemble hybridisation – a new method for exploring sequence dependent fluorescence of dye–nucleic acid conjugates

O. Köhler, D. V. Jarikote and O. Seitz, Chem. Commun., 2004, 2674 DOI: 10.1039/B411877D

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