Issue 21, 2004
From the journal:

Chemical Communications

Synthesis of long Poly(dG)·Poly(dC) DNA using enzymatic reaction†

Shin-ichi Tanaka,a   Masateru Taniguchi,a   Susumu Uchiyama,b   Kiichi Fukuib  and  Tomoji Kawai*a  

* Corresponding authors

a The Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka, Japan
E-mail: kawai@sanken.osaka-u.ac.jp
Fax: #81-6-6875-2440
Tel: #81-6- 6879-8447

b Department of Biotechnology, Osaka University, 2-1 Yamadaoka, Suita, Osaka, Japan
Fax: #81-6-6879-7441
Tel: #81-6-6879-7442

Abstract

Non-defect Poly(dG)·Poly(dC) of 500 bp (170 nm) has been synthesized by using enzymatic reactions and was characterized by its UV spectrum, showing that conjugated π-electrons between base pairs are spread over the DNA molecule suggesting the absence of structural defects.

Graphical abstract: Synthesis of long Poly(dG)·Poly(dC) DNA using enzymatic reaction

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Article information

DOI
https://doi.org/10.1039/B410753E
Article type
Communication
Submitted
05 Jul 2004
Accepted
20 Aug 2004
First published
21 Sep 2004

Chem. Commun., 2004, 2388-2389

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Synthesis of long Poly(dG)·Poly(dC) DNA using enzymatic reaction

S. Tanaka, M. Taniguchi, S. Uchiyama, K. Fukui and T. Kawai, Chem. Commun., 2004, 2388 DOI: 10.1039/B410753E

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