Issue 3, 2004
From the journal:

Chemical Communications

Oxidative coupling of epigallocatechin gallate amplifies antioxidant activity and inhibits xanthine oxidase activity

Motoichi Kurisawa,ab   Joo Eun Chung,ab   Hiroshi Uyama*b  and  Shiro Kobayashi*b  

* Corresponding authors

a Bio-oriented Technology Research Advancement Institution, Japan

b Department of Materials Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan
E-mail: uyama@mat.polym.kyoto-u.ac.jp; kobayasi@mat.polym.kyoto-u.ac.jp
Fax: +81 75 383 2461
Tel: +81 75 383 2460

Abstract

Oxidative coupling of epigallocatechin gallate resulted in great improvement in antioxidant activity such as radical scavenging activity against superoxide anion and in activity to inhibit xanthine oxidase, offering high potential as a therapeutic agent for prevention of xanthine oxidase-induced diseases such as gout.

Graphical abstract: Oxidative coupling of epigallocatechin gallate amplifies antioxidant activity and inhibits xanthine oxidase activity

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Article information

DOI
https://doi.org/10.1039/B312311A
Article type
Communication
Submitted
03 Oct 2003
Accepted
28 Nov 2003
First published
19 Dec 2003

Chem. Commun., 2004, 294-295

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Oxidative coupling of epigallocatechin gallate amplifies antioxidant activity and inhibits xanthine oxidase activity

M. Kurisawa, J. E. Chung, H. Uyama and S. Kobayashi, Chem. Commun., 2004, 294 DOI: 10.1039/B312311A

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