Issue 9, 2003

Deuterated analogues of the free radical trap DEPMPO: synthesis and EPR studies

Abstract

Three analogues of 5-diethoxyphosphoryl-5-methyl-1-pyrroline N-oxide (DEPMPO, 1) labelled with two (1-d2), five (1-d5) or seven (1-d7) 2H were synthesized and used to trap the tert-butylperoxyl radical. The EPR spectra of 1-d2-OOBut and 1-d7-OOBut spin adducts exhibited more straightforward patterns and better signal to noise ratio than those obtained with 1 or 1-d5. The use of the easily available 1-d2 as spin trap could help significantly the analysis of the EPR signals when the signal of either superoxide or alkylperoxyl spin adduct is superimposed with the signals of other spin adducts.

Graphical abstract: Deuterated analogues of the free radical trap DEPMPO: synthesis and EPR studies

Article information

Article type
Paper
Submitted
24 Jan 2003
Accepted
18 Mar 2003
First published
08 Apr 2003

Org. Biomol. Chem., 2003,1, 1591-1597

Deuterated analogues of the free radical trap DEPMPO: synthesis and EPR studies

J. Clément, J. Finet, C. Fréjaville and P. Tordo, Org. Biomol. Chem., 2003, 1, 1591 DOI: 10.1039/B300870C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements