Issue 7, 2003
From the journal:

Organic & Biomolecular Chemistry

Rapid cyanation of aryl iodides in water using microwave promotion

Riina K. Arvela,a   Nicholas E. Leadbeater,*a   Hanna M. Toreniusa  and  Heather Tyeb  

* Corresponding authors

a Department of Chemistry, King's College London, Strand, London, UK
E-mail: nicholas.leadbeater@kcl.ac.uk
Fax: +44 (20) 7848 2810
Tel: +44 (20) 7848 1147

b Evotec OAI, 151 Milton Park, Abingdon, Oxfordshire, UK

Abstract

We show that using water in conjunction with microwave heating it is possible to prepare aryl nitriles from the corresponding aryl iodides rapidly and in high yield without the need for a palladium catalyst.

Graphical abstract: Rapid cyanation of aryl iodides in water using microwave promotion

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Article information

DOI
https://doi.org/10.1039/B211612J
Article type
Paper
Submitted
26 Nov 2002
Accepted
30 Jan 2003
First published
04 Mar 2003

Org. Biomol. Chem., 2003,1, 1119-1121

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Rapid cyanation of aryl iodides in water using microwave promotion

R. K. Arvela, N. E. Leadbeater, H. M. Torenius and H. Tye, Org. Biomol. Chem., 2003, 1, 1119 DOI: 10.1039/B211612J

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