Synthesis of complex α2-3 sialooligosaccharides, including sulfated and fucosylated ones, using Neu5Acα2-3Gal as a building block
Abstract
3-Aminopropyl glycosides of Neu5Acα2-3Galβ, Neu5Acα2-3Galβ1-4GlcNAcβ, Neu5Acα2-3Galβ1-4(6-HSO3)GlcNAcβ, Neu5Acα2-3Galβ1-3GalNAcα, Neu5Acα2-3Galβ1-3(6-HSO3)GalNAcα, Neu5Acα2-3Galβ1-3GlcNAcβ, Neu5Acα2-3Galβ1-3(6-HSO3)GlcNAcβ, Neu5Acα2-3Galβ1-3(Fucα1-4)GlcNAcβ and Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAcβ were synthesised using protected Neu5Acα2-3Gal bromide as a glycosyl donor at the key stage.