N-tert-Butyloxycarbonylamino-3-[Z-α-(2,5-dimethyl-3-thienyl)ethylidene]-4-isopropylidenepyrrolidine-2,5-dione was prepared in 80% yield from the corresponding isomeric hydrazidic acids using N,N'-carbonyldiimidazole, whereas a number of other cyclisation reagents were ineffective.
N,N'-Carbonyldiimidazole as a reagent of choice for the synthesis of thienyl-substituted pyrrolidine-2,5-diones
M. M. Krayushkin, F. M. Stoyanovich and S. V. Shorunov, Mendeleev Commun., 2003, 13, 192 DOI: 10.1070/MC2003v013n04ABEH001761
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