Issue 3, 2003

A stereochemical approach to the Kabachnik–Fields reaction mechanism

Abstract

A comparison of the diastereomeric composition of Kabachnik–Fields reaction products with those of two reactions simulating its stereo-controlling steps showed that only the 'imine' mechanism works in the (MeO)2P(O)H–PhCHO-[(S),(R,S)-H2NCH(Ph)Me] system, like in the phosphite–imine system; in a similar system containing (R,S)-sec-butylamine, additional 'nucleophilic amination' of the initially formed α-hydroxybenzyl phosphonate occurs.

Article information

Article type
Communication
Submitted
16 Apr 2003

Mendeleev Commun., 2003,13, 150-151

A stereochemical approach to the Kabachnik–Fields reaction mechanism

M. N. Dimukhametov, E. V. Bayandina, E. Yu. Davydova, A. T. Gubaidullin and V. A. Alfonsov, Mendeleev Commun., 2003, 13, 150 DOI: 10.1070/MC2003v013n03ABEH001763

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements