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Issue 10, 2003
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Phosphate based glasses for biomedical applications

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Biomaterials and tissue engineering are rapidly expanding fields for research and also commercial exploitation. A greater understanding of the interaction of materials with cells has allowed implant materials to be designed with the aim of promoting a specific biological response. Phosphate-based glasses are a unique group of materials that offer great potential for hard and soft tissue engineering. The move from passive inert implant materials to active degradable materials indicates that phosphate glasses may have a role in tissue engineering. Whilst significant work has been carried out to elucidate the structure of these materials, there is a paucity of data to correlate this information with the physical properties such as dissolution rate. This paper details some of the basic properties of these materials and how these may be exploited in the design of a biomaterial. Also a review of some of the current and potential clinical uses for these materials is included.

Graphical abstract: Phosphate based glasses for biomedical applications

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The article was received on 23 Jun 2003, accepted on 07 Aug 2003 and first published on 14 Aug 2003

Article type: Feature Article
DOI: 10.1039/B307119G
Citation: J. Mater. Chem., 2003,13, 2395-2401

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    Phosphate based glasses for biomedical applications

    J. C. Knowles, J. Mater. Chem., 2003, 13, 2395
    DOI: 10.1039/B307119G

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