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Issue 2, 2003
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Synthesis and evaluation of scintillant-containing poly(oxyethylene glycol) polymer (POP-Sc) supports

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Abstract

Co-polymerisation of α-styryl-poly(ethylene glycol)300, α,ω-bis(styryl)-penta(ethylene glycol) and 2,5-diphenyl-4-(4′-vinylbenzyl)oxazole in varying molar ratios resulted in the production of chemically functionalised scintillant-containing poly(oxyethylene glycol) polymer (POP-Sc) supports. These materials are compatible with both aqueous and organic solvents, and possess the ability to scintillate efficiently in the presence of ionising radiation, even after prolonged and repeated exposure to organic solvents. The utility of POP-Sc supports in both solid-phase peptide chemistry and a functional scintillation proximity assay has been exemplified.

Graphical abstract: Synthesis and evaluation of scintillant-containing poly(oxyethylene glycol) polymer (POP-Sc) supports

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Publication details

The article was received on 23 Oct 2002, accepted on 29 Nov 2002 and first published on 23 Dec 2002


Article type: Paper
DOI: 10.1039/B210421K
J. Mater. Chem., 2003,13, 225-231

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    Synthesis and evaluation of scintillant-containing poly(oxyethylene glycol) polymer (POP-Sc) supports

    M. C. McCairn, A. V. Hine and A. J. Sutherland, J. Mater. Chem., 2003, 13, 225
    DOI: 10.1039/B210421K

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