Issue 5, 2003

Domino reaction of anilines with 3,4-dihydro-2H-pyran catalyzed by cation-exchange resin in water: an efficient synthesis of 1,2,3,4-tetrahydroquinoline derivatives

Abstract

A highly efficient method for the synthesis of 1,2,3,4-tetrahydroquinoline derivatives by using a domino reaction of aromatic amines with 3,4-dihydro-2H-pyran over cation-exchange resin (H form) catalysts in water is described.

Graphical abstract: Domino reaction of anilines with 3,4-dihydro-2H-pyran catalyzed by cation-exchange resin in water: an efficient synthesis of 1,2,3,4-tetrahydroquinoline derivatives

Article information

Article type
Paper
Submitted
23 Apr 2003
First published
07 Aug 2003

Green Chem., 2003,5, 627-629

Domino reaction of anilines with 3,4-dihydro-2H-pyran catalyzed by cation-exchange resin in water: an efficient synthesis of 1,2,3,4-tetrahydroquinoline derivatives

L. Chen and C. Li, Green Chem., 2003, 5, 627 DOI: 10.1039/B304431A

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