Issue 19, 2003
From the journal:

Chemical Communications

Palladium(ii) acetate mediated oxidative cyclization of ω-unsaturated α-cyano ketones. A facile methylenecyclopentane annulation process

Liang-Rern Kung,a   Che-Hao Tu,a   Kak-Shan Shiaa  and  Hsing-Jang Liu*a  

* Corresponding authors

a Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013, Republic of China
E-mail: hjliu@mx.nthu.edu.tw

Abstract

A highly efficient methylenecyclopentane annulation process has been developed based on the Pd(II)-mediated oxidative cyclization of ω-unsaturated α-cyano ketones, readily accessed via the Michael addition of 3-butenylmagnesium bromide with 2-cyano-2-cycloalkenones.

Graphical abstract: Palladium(ii) acetate mediated oxidative cyclization of ω-unsaturated α-cyano ketones. A facile methylenecyclopentane annulation process

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B307114F
Article type
Communication
Submitted
20 Jun 2003
Accepted
12 Aug 2003
First published
01 Sep 2003

Chem. Commun., 2003, 2490-2491

Permissions

Request permissions

Palladium(II) acetate mediated oxidative cyclization of ω-unsaturated α-cyano ketones. A facile methylenecyclopentane annulation process

L. Kung, C. Tu, K. Shia and H. Liu, Chem. Commun., 2003, 2490 DOI: 10.1039/B307114F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements