Issue 16, 2003

First synthesis of the antifungal and antibacterial agent cladobotryal

Abstract

The antifungal and antibacterial agent cladobotryal (1) was synthesized by a convergent route from lactone 5 and aldehyde 12, a key step in the elaboration of the pyridinone ring being conversion of a t-BuOC(O) group on nitrogen into an i-Pr3SiOC(O) group.

Graphical abstract: First synthesis of the antifungal and antibacterial agent cladobotryal

Article information

Article type
Communication
Submitted
30 May 2003
Accepted
27 Jun 2003
First published
09 Jul 2003

Chem. Commun., 2003, 2062-2063

First synthesis of the antifungal and antibacterial agent cladobotryal

D. L. J. Clive and X. Huang, Chem. Commun., 2003, 2062 DOI: 10.1039/B306117E

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