Issue 16, 2003
From the journal:

Chemical Communications

First synthesis of the antifungal and antibacterial agent cladobotryal

Derrick L. J. Clive*a  and  Xiaojun Huanga  

* Corresponding authors

a Chemistry Department, University of Alberta, Edmonton, Alberta, Canada

Abstract

The antifungal and antibacterial agent cladobotryal (1) was synthesized by a convergent route from lactone 5 and aldehyde 12, a key step in the elaboration of the pyridinone ring being conversion of a t-BuOC(O) group on nitrogen into an i-Pr3SiOC(O) group.

Graphical abstract: First synthesis of the antifungal and antibacterial agent cladobotryal

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Article information

DOI
https://doi.org/10.1039/B306117E
Article type
Communication
Submitted
30 May 2003
Accepted
27 Jun 2003
First published
09 Jul 2003

Chem. Commun., 2003, 2062-2063

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First synthesis of the antifungal and antibacterial agent cladobotryal

D. L. J. Clive and X. Huang, Chem. Commun., 2003, 2062 DOI: 10.1039/B306117E

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