Issue 15, 2003

Regio and diastereoselective lactonisation of enolisable 1,3-dicarbonyls by reaction with mesoionic 1,3-oxazolium-5-olates

Abstract

The one-pot reaction of enolisable 1,3-dicarbonyls and N-methyl-1,3-oxazolium-5-olate derivatives provided enol lactones directly in good yield and with excellent regio- and diastereocontrol.

Graphical abstract: Regio and diastereoselective lactonisation of enolisable 1,3-dicarbonyls by reaction with mesoionic 1,3-oxazolium-5-olates

Supplementary files

Article information

Article type
Communication
Submitted
28 Apr 2003
Accepted
10 Jun 2003
First published
23 Jun 2003

Chem. Commun., 2003, 1868-1869

Regio and diastereoselective lactonisation of enolisable 1,3-dicarbonyls by reaction with mesoionic 1,3-oxazolium-5-olates

G. Grassi, F. Risitano, F. Foti, M. Cordaro, G. Bruno and F. Nicolò, Chem. Commun., 2003, 1868 DOI: 10.1039/B304560A

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