Concerted interaction between conjugated double bond CHs and multiple OHs in polyene macrolide antibiotic chainin: weak C–H⋯O interactions responsible for intrinsic molecular assembly

Abstract

The concerted interactions observed between five conjugated double bond CHs and four hydroxy Os in the crystal of chainin, a polyene macrolide antibiotic, clarified the existence of unprecedented, weak C–H⋯O interactions, which is important for forming its intrinsic molecular assembly.