Issue 7, 2003
From the journal:

Chemical Communications

Highly efficient Lewis acid-catalysed Pictet–Spengler reactions discovered by parallel screening†

Natarajan Srinivasana  and  A. Ganesan*a  

* Corresponding authors

a Combinatorial Centre of Excellence, Department of Chemistry, University of Southampton, Southampton SO17 1BJ, United Kingdom
E-mail: ganesan@soton.ac.uk
Fax: +44 2380 596805
Tel: +44 2380 593897;

Abstract

High yielding Lewis acid-catalysed one-pot Pictet–Spengler reactions of tryptophan methyl ester and tryptamine with aliphatic and aromatic aldehydes were achieved in short reaction times with the aid of microwave irradiation.

Graphical abstract: Highly efficient Lewis acid-catalysed Pictet–Spengler reactions discovered by parallel screening

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Article information

DOI
https://doi.org/10.1039/B212063A
Article type
Communication
Submitted
05 Dec 2002
Accepted
19 Feb 2003
First published
11 Mar 2003

Chem. Commun., 2003, 916-917

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Highly efficient Lewis acid-catalysed Pictet–Spengler reactions discovered by parallel screening

N. Srinivasan and A. Ganesan, Chem. Commun., 2003, 916 DOI: 10.1039/B212063A

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