Jump to main content
Jump to site search

Issue 1, 2003
Previous Article Next Article

Site-specific cleavage of human telomerase RNA using PNA-neocuproine·Zn(II) derivatives

Author affiliations

Abstract

Here we report the synthesis of a novel PNA based neocuproine·Zn RNA cleaving agent; we demonstrate that such agents sequence specifically cleave a synthetic RNA target and in particular the RNA component of human telomerase.

Graphical abstract: Site-specific cleavage of human telomerase RNA using PNA-neocuproine·Zn(ii) derivatives

Back to tab navigation

Supplementary files

Publication details

The article was received on 16 Oct 2002, accepted on 11 Nov 2002 and first published on 26 Nov 2002


Article type: Communication
DOI: 10.1039/B210135A
Citation: Chem. Commun., 2003,0, 36-37

  •   Request permissions

    Site-specific cleavage of human telomerase RNA using PNA-neocuproine·Zn(II) derivatives

    A. Whitney, G. Gavory and S. Balasubramanian, Chem. Commun., 2003, 0, 36
    DOI: 10.1039/B210135A

Search articles by author

Spotlight

Advertisements