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Issue 7, 2002
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Photoremovable protecting groups: reaction mechanisms and applications

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Abstract

Photolabile protecting groups enable biochemists to control the release of bioactive compounds in living tissue. ‘Caged compounds’ (photoactivatable bioagents) have become an important tool to study the events that follow chemical signalling in, e.g., cell biology and the neurosciences. The possibilities are by no means exhausted. Progress will depend on the development of photoremovable protecting groups that satisfy the diverse requirements of new applications—a challenging task for photochemists.

Graphical abstract: Photoremovable protecting groups: reaction mechanisms and applications

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Publication details

The article was received on 21 Jan 2002, accepted on 01 May 2002 and first published on 06 Jun 2002


Article type: Perspective
DOI: 10.1039/B200777K
Citation: Photochem. Photobiol. Sci., 2002,1, 441-458

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    Photoremovable protecting groups: reaction mechanisms and applications

    A. P. Pelliccioli and J. Wirz, Photochem. Photobiol. Sci., 2002, 1, 441
    DOI: 10.1039/B200777K

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