Issue 14, 2002
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

A chemoenzymatic synthesis of the styryllactone (+)-goniodiol from naphthalene

Martin G. Banwell,*a   Mark J. Coster,a   Ochitha P. Karunaratnea  and  Jason A. Smitha  

* Corresponding authors

a Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 0200, Australia
E-mail: mgb@rsc.anu.edu.au

Abstract

The enantiomerically pure cis-1,2-diol 2, which is obtained by microbial oxidation of naphthalene, has been converted, via a sequence of reactions including oxidative C–C bond cleavage, decarbonylation and ring-closing metathesis steps, into the natural product (+)-goniodiol (1).

Graphical abstract: A chemoenzymatic synthesis of the styryllactone (+)-goniodiol from naphthalene

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Article information

DOI
https://doi.org/10.1039/B205230J
Article type
Communication
Submitted
29 May 2002
Accepted
12 Jun 2002
First published
25 Jun 2002

J. Chem. Soc., Perkin Trans. 1, 2002, 1622-1624

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A chemoenzymatic synthesis of the styryllactone (+)-goniodiol from naphthalene

M. G. Banwell, M. J. Coster, O. P. Karunaratne and J. A. Smith, J. Chem. Soc., Perkin Trans. 1, 2002, 1622 DOI: 10.1039/B205230J

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