Issue 13, 2002

Efficient synthesis of functionalized 3H-pyrrolo[1,2-a]indoles

Abstract

Dialkyl 9-chloro-3H-pyrrolo[1,2-a]indole-2,3-dicarboxylates are obtained in excellent yields from the 1 ∶ 1 ∶ 1 addition reaction between triphenylphosphine, dialkyl acetylenedicarboxylates and 3-chloroindole-2-carbaldehyde; dimethyl 9-chloro-3H-pyrrolo[1,2-a]indole-2,3-dicarboxylate is converted to dimethyl 9-oxo-9H-pyrrolo[1,2-a]indole-2,3-dicarboxylate.

Graphical abstract: Efficient synthesis of functionalized 3H-pyrrolo[1,2-a]indoles

Article information

Article type
Communication
Submitted
08 May 2002
Accepted
28 May 2002
First published
10 Jun 2002

J. Chem. Soc., Perkin Trans. 1, 2002, 1517-1519

Efficient synthesis of functionalized 3H-pyrrolo[1,2-a]indoles

I. Yavari, M. Adib and M. H. Sayahi, J. Chem. Soc., Perkin Trans. 1, 2002, 1517 DOI: 10.1039/B204433C

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