Issue 10, 2002

Synthesis of fluorinated 2-phenyl-4-quinolones from pyrrole-2,3-diones

Abstract

A series of substituted 2-phenyl-4-quinolones 8–11 have been synthesized in good yields via flash vacuum thermolysis (FVT) of 1-aryl-4-cyano-5-phenylpyrrole-2,3-diones 7a–e and 1-aryl-4-methoxycarbonyl-5-phenylpyrrole-2,3-diones 7f–j. The pyrrolediones 7 were prepared from amines 3 and benzoylacetonitriles 5a–e or methyl 3-arylamino-3-phenylprop-2-enoates 5f–j.

Graphical abstract: Synthesis of fluorinated 2-phenyl-4-quinolones from pyrrole-2,3-diones

Supplementary files

Article information

Article type
Paper
Submitted
28 Feb 2002
Accepted
11 Apr 2002
First published
23 Apr 2002

J. Chem. Soc., Perkin Trans. 1, 2002, 1232-1235

Synthesis of fluorinated 2-phenyl-4-quinolones from pyrrole-2,3-diones

V. V. R. Rao and C. Wentrup, J. Chem. Soc., Perkin Trans. 1, 2002, 1232 DOI: 10.1039/B202128E

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