Issue 6, 2002
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Synthesis of (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate, a key intermediate in the biosynthesis of isoprenoids

Jane L. Warda  and  Michael H. Beale*a  

* Corresponding authors

a IACR-Long Ashton Research Station, Department of Agricultural Sciences, University of Bristol, Long Ashton, Bristol, UK
E-mail: mike.beale@bbsrc.ac.uk

Abstract

(2E)-4-Hydroxy-3-methylbut-2-enyl diphosphate, (HMBPP) has been synthesised by regioselective hydroxylation and diphosphorylation of dimethylallyl alcohol.

Graphical abstract: Synthesis of (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate, a key intermediate in the biosynthesis of isoprenoids

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Article information

DOI
https://doi.org/10.1039/B200712F
Article type
Communication
Submitted
21 Jan 2002
Accepted
19 Feb 2002
First published
26 Feb 2002

J. Chem. Soc., Perkin Trans. 1, 2002, 710-712

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Synthesis of (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate, a key intermediate in the biosynthesis of isoprenoids

J. L. Ward and M. H. Beale, J. Chem. Soc., Perkin Trans. 1, 2002, 710 DOI: 10.1039/B200712F

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