Issue 2, 2002

Synthesis of nornicotine, nicotine and other functionalised derivatives using solid-supported reagents and scavengers

Abstract

The sequential use of solid-supported reagents and scavengers has led to an efficient synthesis of the natural products nornicotine 1, nicotine 2 and further fuctionalised derivatives. Also reported is a diastereoselective route to both enantiomers of nicotine 2.

Graphical abstract: Synthesis of nornicotine, nicotine and other functionalised derivatives using solid-supported reagents and scavengers

Supplementary files

Article information

Article type
Paper
Submitted
17 Oct 2001
Accepted
20 Nov 2001
First published
17 Dec 2001

J. Chem. Soc., Perkin Trans. 1, 2002, 143-154

Synthesis of nornicotine, nicotine and other functionalised derivatives using solid-supported reagents and scavengers

I. R. Baxendale, G. Brusotti, M. Matsuoka and S. V. Ley, J. Chem. Soc., Perkin Trans. 1, 2002, 143 DOI: 10.1039/B109482N

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements