Issue 1, 2002
From the journal:

Mendeleev Communications

Kinetic resolution of (±)-2-methyl-1,2,3,4-tetrahydroquinoline and (±)-2-methylindoline

Victor P. Krasnov,   Galina L. Levit,   Irina N. Andreeva,   Alexander N. Grishakov,   Valerii N. Charushin  and  Oleg N. Chupakhin  

Abstract

The acylation of racemic 2-methyl-1,2,3,4-tetrahydroquinoline and 2-methylindoline by (S)-naproxen acyl chloride resulted in their kinetic resolution with the predominant formation of (S,S)-diastereoisomeric amides (de78–76%), recrystallisation of which fol-lowed by acid hydrolysis gave individual (S)-isomers of heterocyclic amines.

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Article information

DOI
https://doi.org/10.1070/MC2002v012n01ABEH001545
Article type
Paper

Mendeleev Commun., 2002,12, 27-28

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Kinetic resolution of (±)-2-methyl-1,2,3,4-tetrahydroquinoline and (±)-2-methylindoline

V. P. Krasnov, G. L. Levit, I. N. Andreeva, A. N. Grishakov, V. N. Charushin and O. N. Chupakhin, Mendeleev Commun., 2002, 12, 27 DOI: 10.1070/MC2002v012n01ABEH001545

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