Issue 4, 2002
From the journal:

Green Chemistry

Microwave enhanced synthesis of acridines. A new aspect in the Bernthsen reaction

Julio A. Seijas,*a   M. Pilar Vázquez-Tato,*a   M. Montserrat Martíneza  and  Jacobo Rodríguez-Pargaa  

* Corresponding authors

a Departamento de Química Orgánica, Universidad de Santiago de Compostela, Facultad de Ciencias, Aptdo. 280, Lugo, Spain
E-mail: qoseijas@lugo.usc.es or pilarvt@lugo.usc.es

Abstract

The Bernthsen reaction is studied using microwaves as the heat source. This leads to acridines with aromatic and aliphatic substituents in position 9, shortening reaction times and increasing yields, with a reduction in Lewis acid catalyst (ZnCl2), allowing a more environmentally friendly reaction.

Graphical abstract: Microwave enhanced synthesis of acridines. A new aspect in the Bernthsen reaction

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Article information

DOI
https://doi.org/10.1039/B204243F
Article type
Paper
Submitted
01 May 2002
First published
12 Jul 2002

Green Chem., 2002,4, 390-391

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Microwave enhanced synthesis of acridines. A new aspect in the Bernthsen reaction

J. A. Seijas, M. P. Vázquez-Tato, M. M. Martínez and J. Rodríguez-Parga, Green Chem., 2002, 4, 390 DOI: 10.1039/B204243F

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