A green chemical method for the direct conversion of alcohol tetrahydropyranyl ethers into the corresponding acetates

Abstract

Alcohol tetrahydropyranyl ethers are readily converted into the corresponding acetates by the reaction with acetyl bromide in acetonitrile. Using various substituted acetyl chlorides with an equimolar amount of sodium iodide, tetrahydropyranyl ethers can be also transformed into the corresponding substituted acetates in high yields. This clean synthesis is a significant method for atom economy.