Issue 22, 2002
From the journal:

Chemical Communications

Alternate stranded triplex formation of chimeric DNA composed of tandem α- and β-anomeric strands

Kazuo Shinozuka,*a   Noritake Matsumoto,a   Hideo Suzuki,a   Tomohisa Moriguchia  and  Hiroaki Sawaia  

* Corresponding authors

a Department of Chemistry, Faculty of Engineering, Gunma University, 1-5-1 Tenjin-cho, Kiryu, Japan
E-mail: sinozuka@chem.gunma-u.ac-jp
Fax: +81 277-30-1321
Tel: +81 277-30-1320

Abstract

A chimeric oligoDNA composed of a natural β-anomeric oligonucleotide portion and an unnatural α-anomeric oligonucleotide portion forms an alternate stranded triplex possessing enhanced thermal stability compared to the triplexes composed of the parental oligomers.

Graphical abstract: Alternate stranded triplex formation of chimeric DNA composed of tandem α- and β-anomeric strands

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Article information

DOI
https://doi.org/10.1039/B208793F
Article type
Communication
Submitted
10 Sep 2002
Accepted
09 Oct 2002
First published
23 Oct 2002

Chem. Commun., 2002, 2712-2713

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Alternate stranded triplex formation of chimeric DNA composed of tandem α- and β-anomeric strands

K. Shinozuka, N. Matsumoto, H. Suzuki, T. Moriguchi and H. Sawai, Chem. Commun., 2002, 2712 DOI: 10.1039/B208793F

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