Issue 13, 2002

A screening system for enantioselective enzymes based on differential cell growth

Abstract

The esterase-catalyzed enantioselective hydrolysis of the fluoroacetate of pantolactone leads to fluoroacetic acid, a toxic compound which inhibits the growth of esterase-producing yeast; this forms the basis of an ee-assay.

Graphical abstract: A screening system for enantioselective enzymes based on differential cell growth

Article information

Article type
Communication
Submitted
22 Apr 2002
Accepted
21 May 2002
First published
05 Jun 2002

Chem. Commun., 2002, 1428-1429

A screening system for enantioselective enzymes based on differential cell growth

M. T. Reetz and C. J. Rüggeberg, Chem. Commun., 2002, 1428 DOI: 10.1039/B203916H

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