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A stable interface between two insoluble currents in a microchannel reactor has been obtained by selecting the solvents and adjusting the flow rate; titania particles with a size of less than 10 nm could be prepared continously on this interface; this new method shows great advantage for the control and measurement of particle sizes.

Graphical abstract: Preparation of titania particles utilizing the insoluble phase interface in a microchannel reactor

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