Issue 13, 2002
From the journal:

Chemical Communications

Interactions of phenanthridinium–nucleobase conjugates with polynucleotides in aqueous media. Recognition of poly U†

Iva Juranović,b   Zlatko Meić,a   Ivo Piantanida,*a   Lidija-Marija Tumira  and  Mladen Žinić*a  

* Corresponding authors

a Laboratory of Supramolecular and Nucleoside Chemistry, Department of Chemistry and Biochemistry, Rudjer Boskovic Institute, HR 10000 Zagreb, Croatia

b Laboratory of Analytical Chemistry, Department of Chemistry, Faculty of Science, Strossmayerov trg 14, HR 10000 Zagreb, Croatia

Abstract

Adenine containing conjugates 4 and 5 exhibit specific spectroscopic changes and two orders of magnitude higher affinity toward poly U than uracil conjugates 2 and 3 and the reference compound 1 due to the existence of specific interactions between adenine and uracil, possibly Watson-Crick hydrogen bonding between the bases stacked on the phenanthridinium moiety.

Graphical abstract: Interactions of phenanthridinium–nucleobase conjugates with polynucleotides in aqueous media. Recognition of poly U

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Article information

DOI
https://doi.org/10.1039/B202615E
Article type
Communication
Submitted
20 Mar 2002
Accepted
14 May 2002
First published
05 Jun 2002

Chem. Commun., 2002, 1432-1433

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Interactions of phenanthridinium–nucleobase conjugates with polynucleotides in aqueous media. Recognition of poly U

I. Juranović, Z. Meić, I. Piantanida, L. Tumir and M. Žinić, Chem. Commun., 2002, 1432 DOI: 10.1039/B202615E

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