Issue 10, 2002
From the journal:

Chemical Communications

Stereoselective cycloadditions of chiral acyl-nitroso compounds; selective reactions of ring-cleaved cycloadducts leading to a new approach to polyoxamic acid

Adrian G. Pepper,†a   Garry Proctera  and  Martyn Voyleb  

a Department of Chemistry and Applied Chemistry, University of Salford, Salford, UK

b SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, Third Avenue, Essex, Harlow, UK

Abstract

Diesters obtained from diacids produced by oxidative ring cleavage of cycloadducts derived from acyl-nitroso compounds and cyclic 1,3-dienes undergo highly regioselective hydrolysis on reaction with lithium hydroperoxide, which allows for easy differentiation of the carboxyl groups leading to a new approach to polyoxamic acid.

Graphical abstract: Stereoselective cycloadditions of chiral acyl-nitroso compounds; selective reactions of ring-cleaved cycloadducts leading to a new approach to polyoxamic acid

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B201645C
Article type
Communication
Submitted
13 Feb 2002
Accepted
03 Apr 2002
First published
15 Apr 2002

Chem. Commun., 2002, 1066-1067

Permissions

Request permissions

Stereoselective cycloadditions of chiral acyl-nitroso compounds; selective reactions of ring-cleaved cycloadducts leading to a new approach to polyoxamic acid

A. G. Pepper, G. Procter and M. Voyle, Chem. Commun., 2002, 1066 DOI: 10.1039/B201645C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements